Table 1. Development of EAE.

Group	Incidence	Day of disease onset	Maximum clinical score	Score>3
Wild type	14 of 14(100%)	15.0±0.9	3.1 (±0.4)	9 of 14
heterozygote	14 of 15(93.3%)	14.2±0.4	2.4 (±0.3)	7 of 15
Gαq-KO	4 of 5(80%)	11.5±0.3	1.1 (±0.4)*	0 of 5

Development of MOG_35–55-induced EAE. Incidence reflects the number of mice that developed EAE relative to the total mice in a group; Day of disease onset is presented in days (mean±s.e.m.); Maximum clinical score is the average of the highest score reached by each mouse in a group (mean±SEM.); Score>3 shows the number of mice achieving an EAE score of greater than 3 relative to the total mice in a group. *P<0.05, versus wild type (Student’s t-test).