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. 2017 May 11;116(12):1536–1543. doi: 10.1038/bjc.2017.127

Table 2. Regression model estimating associations between diagnostic interval and number of ‘competing demand’ and/or ‘alternative explanation’ conditions.

  Coeff. (95% CI) P-value Exponentiated coeff. (95% CI) Diagnostic interval change in days (95% CI)a
Female gender 0.02 (−0.05, 0.09) 0.544 1.02 (0.95, 1.09) 2 (−3, 7)
Age group (years)b 0.07 (0.05, 0.09) <0.001    
 40–59 (reference) 0.00 1.00  
 60–64 −0.13 (−0.27, 0.02) 0.083 0.88 (0.76, 1.02) −9 (−18, 1)
 65–69 0.05 (−0.09, 0.18) 0.505 1.05 (0.91, 1.20) 4 (−7, 15)
 70–74 0.06 (−0.08, 0.19) 0.395 1.06 (0.93, 1.21) 5 (−6, 16)
 75–79 0.10 (−0.03, 0.23) 0.132 1.11 (0.97, 1.26) 8 (−2, 20)
 80–84 0.32 (0.19, 0.45) <0.001 1.38 (1.21, 1.57) 29 (16, 44)
 85+ 0.34 (0.21, 0.48) <0.001 1.41 (1.23, 1.62) 31 (17, 47)
No. of 'competing demand' conditionsb 0.09 (0.06, 0.12) <0.001    
 None (reference) 0.00 1.00  
 One 0.12 (0.03, 0.21) 0.009 1.13 (1.03, 1.24) 10 (2, 18)
 Two 0.20 (0.10, 0.30) <0.001 1.22 (1.11, 1.34) 17 (8, 26)
 Three 0.30 (0.18, 0.41) <0.001 1.34 (1.20, 1.51) 26 (15, 39)
 Four or more 0.35 (0.20, 0.49) <0.001 1.41 (1.22, 1.63) 32 (17, 49)
No. of 'alternative explanation' conditionsb 0.09 (0.03, 0.14) 0.003    
 None (reference) 0.00 1.00  
 One 0.12 (0.04, 0.19) 0.003 1.12 (1.04, 1.21) 9 (3, 16)
 Two or more 0.13 (−0.01, 0.27) 0.061 1.14 (0.99, 1.32) 11 (0, 24)
Inflammatory bowel disease 0.29 (0.17, 0.41) <0.001 1.34 (1.18, 1.51) 26 (14, 39)
Non-colorectal cancer 0.11 (−0.05, 0.28) 0.173 1.12 (0.95, 1.32) 9 (−4, 24)

Abbreviation: CI=confidence interval.

a

Calculated using the geometric mean (as used by the log-tranformed regression model) of 76.71.

b

Sensitivity analyses entered these covariates as ordinal variables to assess their global effects, which are reported above the effects of their separate levels.