Table 1. Concordance of best responses.
Overlap-MDS/MPN criteria |
||||||
---|---|---|---|---|---|---|
Responders |
Non-responders |
|||||
No. of patients | IWG-2006 | Overlap-MDS/MPN | No. of patients | IWG-2006 | Overlap-MDS/MPN | |
IWG-2006 criteria | ||||||
Responders | 45 (57%) | 0 | ||||
10 | CR | CR | ||||
10 | mCR-HI | OMR-CB | ||||
6 | mCR | OMR | ||||
11 | SD-HI | SD-CB | ||||
1 | CR | OMR-CB | ||||
1 | CR | OMR | ||||
4 | CR | SD-CB | ||||
2 | mCR | OMR-CB | ||||
Non-responders | 11 (14%) | 23 (29%) | ||||
1 | SD | OMR | 10 | SD | SD | |
1 | SD | PMR | 4 | PD | PD | |
3 | SD | SD-CB | 9 | PD | SD | |
1 | PD | OMR-CB | ||||
4 | PD | OMR | ||||
1 | PD | SD-CB |
Abbreviations: CB, clinical benefit; CR, complete response; HI, haematologic improvement; mCR, marrow complete response; OMR, optimal marrow response; PD, progressive disease; PMR, partial marrow response; SD, stable disease.