Figure 1.

Both trace and delay fear conditioning undergo reconsolidation in the amygdala following a standard, conditional stimulus (CS)-only retrieval trial in a novel context. (a) Experimental timeline. (b) Mean time spent freezing during each period (Baseline, BL; CS presentation, CS; post-CS, post) of the retrieval session. (c) Freezing during the CS test. Intra-amygdala ANI disrupted reconsolidation of both delay and trace fear conditioning. Data are presented as mean±SEM **p<0.01; n=10–16/group. ACSF, artificial cerebrospinal fluid (vehicle); AMY, amygdala; ANI, aniosmycin (protein synthesis inhibitor); BL, baseline; CS, conditional stimulus.