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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Hum Pathol. 2017 Jan 30;64:19–27. doi: 10.1016/j.humpath.2017.01.003

Table 1.

Demographic and genetic characteristics of ALCLs in the present study

WHO subtype
All cases
ALK-positive ALK-negative* Primary cutaneous**
N 22 62 32 116
Age (years)
 Mean 29 62 62 56
 Range 6–74 24–87 13–93 6–93
Sex
 Male 18 40 17 75
 Female 4 22 15 41
Genetics
 DUSP22 rearrangement
  Present 0 19 13 32
  Absent 20 43 19 82
  Not done 2 0 0 2
 TP63 rearrangement
  Present 0 8 2 10
  Absent 22 54 30 106
  Not done 0 0 0 0

Abbreviations: ALCL: anaplastic large cell lymphoma; ALK: anaplastic lymphoma kinase; WHO: World Health Organization.

*

In 1 case of systemic ALK-negative ALCL the specimen available for analysis was a skin biopsy, though the patient had documented systemic disease.

**

In 3 cases of primary cutaneous ALCL the specimens available for analysis were locoregional lymph nodes, though the patients had documented primary cutaneous disease.