Fig. 3.
Vulvar intraepithelial neoplasia, differentiated type (dVIN). (A) Partial thickness dysplasia with retention of keratohyaline granules; (B) basal atypia, nuclei with prominent nucleoli and intercellular bridges; (C) hypereosinophilia and premature keratinisation; (D) irregular branching and anastomoses of rete ridges; (E) pseudoinvasion, regular spacing of nests with rounded contours (arrows); (F) paradoxical maturation suggestive of early invasion.