Table 2. CTSL and CTSB in relation to clinical parameters in patients with liver cirrhosis.
| Parameters |
CTSL |
CTSB |
||||
|---|---|---|---|---|---|---|
| N | ρ | P | N | ρ | P | |
| Age | 51 | 0.13 | NS | 51 | 0.05 | NS |
| Hemoglobin | 51 | −0.08 | NS | 48 | 0.05 | NS |
| White blood count (cells/ml) | 51 | −0.03 | NS | 50 | −0.08 | NS |
| Neutrophil count | 49 | 0.47** | 0.01 | 45 | 0.19 | NS |
| Prothrombin time | 49 | −0.04 | NS | 45 | 0.23 | NS |
| Platelet count | 51 | −0.08 | NS | 50 | 0.07 | NS |
| Sodium | 51 | −0.03 | NS | 50 | −0.20 | NS |
| Potassium | 51 | −0.09 | NS | 50 | 0.06 | NS |
| Urea | 51 | 0.23 | NS | 49 | −0.01 | NS |
| Creatinine | 51 | 0.16 | NS | 51 | −0.03 | NS |
| Total bilirubin | 51 | 0.38** | 0.04 | 50 | 0.23* | 0.05 |
| Aspartate aminotransferase | 51 | 0.25 | NS | 50 | 0.21 | NS |
| Alanine aminotransferase | 51 | 0.19 | NS | 51 | −0.06 | NS |
| Alkaline phosphatase | 51 | 0.08 | NS | 51 | 0.04 | NS |
| Serum total protein | 51 | 0.15 | NS | 51 | 0.12 | NS |
| Serum albumin | 51 | −0.16 | NS | 51 | −0.28* | 0.04 |
| Child–Pugh stage | 65 | 0.52** | <0.01 | 65 | 0.68** | <0.01 |
| CTSL | — | — | — | 47 | 0.34* | 0.02 |
| CTSB | 47 | 0.34* | 0.02 | — | — | — |
CTSB, cathepsin B; CTSL, cathepsin L; NS, not significant.
Correlations of plasma CTSL and CTSB with other clinical parameters were analyzed by Spearman rank correlation test, and data are presented for all the patients. For correlations of Child–Pugh stage with CTSL and CTSB, control values were also included. *Indicates P value <0.05. **P≤0.01.