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. 2017 Jul 20;12(7):e0178889. doi: 10.1371/journal.pone.0178889

Table 3. Characteristics of the patients who suffer an APS event during the follow up versus patients without APS events.

N.S.: Non significant.


APS events
N = 45

Without events
N = 420
   
CONDITION N % /SE(range) N % /SE (range) p OR
    Sex (male) 20  (44.4%) 99  (23.6%) 0.002 2.59
    Age (years) 60.4 2.0((25–75) 48.8 0.7(18–75) <0.001
    Hypertension 23  (51.1%) 111  (26.4%) <0.001 2.91
    Diabetes mellitus 11  (24.4%) 34  (8.1%) <0.001 3.67
        Type 1 Diabetes 2  (4.4%) 2  (0.5%) 0.048
        Type 2 Diabetes 9  (20%) 32  (7.6%) 0.005
    Dyslipidemia 14  (31.1%) 66  (15.7%) 0.009 2.42
    IgA-aB2GP1 positive 38  (84.4%) 206  (49%) <0.001 5.64
    Smoker 3  (6.7%) 30  (7.1%) N.S.
    Ex-smoker 3  (6.7%) 15  (3.6%) N.S.
    Familial antecedents of APS events 0  (0%) 5  (1%) N.S.
Aim of the study / underlying disease
    Health screening (without pathology) 8  (17.8%) 62  (14.8%) N.S.
    Systemic autoinmune diseases 9  (20%) 137  (32.6%) N.S.
        Systemic lupus erythematosus 6  (13.3%) 63  (15%) N.S.
        Rheumatoid arthritis 1  (2.2%) 30  (7.1%) N.S.
        Mixed conective disease 0  (0%) 2  (0.5%) N.S.
        Systemic sclerosis 2  (4.4%) 25  (6%) N.S.
        Sjögren's syndrome 0  (0%) 17  (4%) N.S.
    Infertility and obstetric studies 2  (4.4%) 20  (4.8%) N.S.
    Ankylosing spondylitis 0  (0%) 4  (1%) N.S.
    Muscular diseases 2  (4.4%) 8  (1.9%) N.S.
    Non-systemic autoimmunity 2  (4.4%) 16  (3.8%) N.S.
    Neurologic evaluation 1  (2.2%) 18  (4.3%) N.S.
    Endocrinology evaluation 0  (0%) 5  (1.2%) N.S.
    Venous insufficiency 2  (4.4%) 12  (2.9%) N.S.
    Other illness 19  (42.2%) 138  (32.9%) N.S.