Table 3. Characteristics of the patients who suffer an APS event during the follow up versus patients without APS events.
APS events N = 45 |
Without events N = 420 |
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---|---|---|---|---|---|---|
CONDITION | N | % /SE(range) | N | % /SE (range) | p | OR |
Sex (male) | 20 | (44.4%) | 99 | (23.6%) | 0.002 | 2.59 |
Age (years) | 60.4 | 2.0((25–75) | 48.8 | 0.7(18–75) | <0.001 | — |
Hypertension | 23 | (51.1%) | 111 | (26.4%) | <0.001 | 2.91 |
Diabetes mellitus | 11 | (24.4%) | 34 | (8.1%) | <0.001 | 3.67 |
Type 1 Diabetes | 2 | (4.4%) | 2 | (0.5%) | 0.048 | — |
Type 2 Diabetes | 9 | (20%) | 32 | (7.6%) | 0.005 | — |
Dyslipidemia | 14 | (31.1%) | 66 | (15.7%) | 0.009 | 2.42 |
IgA-aB2GP1 positive | 38 | (84.4%) | 206 | (49%) | <0.001 | 5.64 |
Smoker | 3 | (6.7%) | 30 | (7.1%) | N.S. | — |
Ex-smoker | 3 | (6.7%) | 15 | (3.6%) | N.S. | — |
Familial antecedents of APS events | 0 | (0%) | 5 | (1%) | N.S. | — |
Aim of the study / underlying disease | ||||||
Health screening (without pathology) | 8 | (17.8%) | 62 | (14.8%) | N.S. | — |
Systemic autoinmune diseases | 9 | (20%) | 137 | (32.6%) | N.S. | — |
Systemic lupus erythematosus | 6 | (13.3%) | 63 | (15%) | N.S. | — |
Rheumatoid arthritis | 1 | (2.2%) | 30 | (7.1%) | N.S. | — |
Mixed conective disease | 0 | (0%) | 2 | (0.5%) | N.S. | — |
Systemic sclerosis | 2 | (4.4%) | 25 | (6%) | N.S. | — |
Sjögren's syndrome | 0 | (0%) | 17 | (4%) | N.S. | — |
Infertility and obstetric studies | 2 | (4.4%) | 20 | (4.8%) | N.S. | — |
Ankylosing spondylitis | 0 | (0%) | 4 | (1%) | N.S. | — |
Muscular diseases | 2 | (4.4%) | 8 | (1.9%) | N.S. | — |
Non-systemic autoimmunity | 2 | (4.4%) | 16 | (3.8%) | N.S. | — |
Neurologic evaluation | 1 | (2.2%) | 18 | (4.3%) | N.S. | — |
Endocrinology evaluation | 0 | (0%) | 5 | (1.2%) | N.S. | — |
Venous insufficiency | 2 | (4.4%) | 12 | (2.9%) | N.S. | — |
Other illness | 19 | (42.2%) | 138 | (32.9%) | N.S. | — |