Table 1. Characteristics of randomized controlled trials published in the three highest-impact journals between January 1, 2010 and December 31, 2015.
| n = 154 | |
|---|---|
| Journal | |
| Neurology | 86 |
| Lancet Neurology | 82 |
| Annals of Neurology | 12 |
| Funding Source | |
| Industry/Corporate | 71 |
| Public | 60 |
| Private | 21 |
| Mixed | 11 |
| None Disclosed | 1 |
| Registry | |
| Australian New Zealand Clinical Trials Registry | 2 |
| ClinicalTrials.gov | 158 |
| EudraCT | 4 |
| ISRCTN | 11 |
| Netherlands Trial Registry | 4 |
| Dutch Trial Registry | 1 |
| Time of Registration | |
| Registered before or during patient enrollment | 163 |
| Retrospectively registered | 17 |
| Publication Year | |
| 2011 | 26 |
| 2012 | 37 |
| 2013 | 28 |
| 2014 | 49 |
| 2015 | 38 |
| 2016 | 2 |
| Number of Patients Enrolled | |
| <100 | 72 |
| 100–199 | 32 |
| 200–499 | 36 |
| >500 | 40 |