Skip to main content
. 2017 Jul 20;12(7):e0180986. doi: 10.1371/journal.pone.0180986

Table 4. Year-by-year frequency of major discrepancies between published and registered outcomes in RCTs registered before or during patient enrollment (n = 181), and the effect of these discrepancies on the statistical significance of published outcomes, by year.

Publication year No. of major discrepancies No. of evaluable discrepancies, No. of evaluable discrepancies whose discrepancies favor statistically significant results
2011 25 14 56% 7 50%
2012 42 19 45% 16 84%
2013 20 10 50% 3 30%
2014 62 25 40% 19 76%
2015 27 13 48% 7 54%
2016 4 2 50% 0 0%
Total 180 82 46% 52 63%