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. 2017 Jul 20;12(7):e0181256. doi: 10.1371/journal.pone.0181256

Fig 3. Predicted protein-protein and protein-chemical interactions for comparisons involving IL-4.

Fig 3

The comparisons showed overall down regulation for both strains. The comparison infected with VR-2332 (Comp_7 and Comp_18) showed downregulation of more immune related genes and interactions, while the HP-PRRSV (Comp_12 and Comp_24) showed downregulation of more genes and networks related to structural integrity and immune signaling. Gene (nodes) represented by circles and the color of the connecting lines (edges) defines the molecular action of the connected nodes. Direction of expression based on rlogFC threshold of ≥ -2 or 2.