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. 2017 Jul 20;12(7):e0180844. doi: 10.1371/journal.pone.0180844

Fig 5. miR-200c regulates HMGB1 expression in lung cancer cells.

Fig 5

Alignment of the sequence of miR-200c with that of the 3′untranslated region of HMGB1 showing the putative binding sites (A). Real-time PCR analysis of miR-200c expression in A459 cells after transfection with a miR-200c mimic or inhibitor (B). After transfection, HMGB1 expression was analysed by real-time PCR (C), western blotting (D), and immunocytochemical staining (E). *p <0.05 as compared to the control group. α-Tubulin was used as a loading control.