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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Neurobiol Aging. 2017 Feb 16;54:1–9. doi: 10.1016/j.neurobiolaging.2017.02.005

Figure 2.

Figure 2

Longitudinal difference in clinical scales over two years related to the change in factor scores. Clinical scales included the A) Mini-Mental State Examination (MMSE), the B) Alzheimer’s Disease Assessment Scale (ADAS-Cog 13-item scale) and the C) Clinical Dementia Rating – Sum of Boxes (CDR-SB). D) The correlation between the difference in ‘age- and vascular-related’ factor (AVF) and the difference in ‘neurodegenerative’ factor (NDF) is also shown. Pearson’s correlation coefficients and associated p-values are shown. Individuals with MCI who converted to AD during the two-year follow-up are shown in gray while those who did not convert are shown in white. Difference defined as value at follow-up minus value at baseline. All significant relationships remain significant when correcting for all covariates as detailed in the models, but uncorrected data is presented here to further support the hypothesis that longitudinal cognitive decline is related to a change in the factor scores.