Illustration of the inverse relation between circulatory arrest and psychomotor development index in infants at one-year post the neonatal arterial switch operation for complete transposition of the great arteries.8 Reprinted with permission from Bellinger DC, Jonas RA, Rappaport LA, Wypij D, Wernovsky G, Kuban KC, Barnes PD, Holmes GL, Hickey PR, Strand RD, Walsh AZ, Helmers SL, Constantinou JE, Carrazana EJ, Mayer JE, Hanley FL, Castaneda AR, Ware JH, Newburger JW. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. The New England Journal of Medicine. 1995;332:549–555.