Table 1.

Characteristics of Cases and Controls

	Discovery Set			Training Set				Validation Set
	Controls	Serous Cases	Chi-square	Controls	Benign Controls	Serous Cases	Chi-square	Controls	Serous Cases	Chi-square
			p-value*				p-value*			p-value*
	(N=30) N (%)	(N=30) N (%)		(N=30) N (%)	(N=30) N (%)	(N=30) N (%)		(N=32) N (%)	(N=34) N (%)
Age
<50	6 (20.0%)	6 (20.0%)	0.99	12 (40.0%)	12 (40.0%)	11 (36.7%)	0.99	1 (3.1%)	2 (5.9%)	0.85
50–60	12 (40.0%)	12 (40.0%)		11 (36.7%)	11 (36.7%)	11 (36.7%)		10 (31.2%)	11 (32.4%)
>60	12 (40.0%)	12 (40.0%)		7 (23.3%)	7 (23.3%)	8 (26.7%)		21 (65.6%)	21 (61.8%)
Menopausal status
Pre	8 (26.7%)	6 (20.0%)	0.54	13 (43.3%)	10 (33.3%)	10 (33.3%)	0.65	3 (9.4%)	3 (8.8%)	0.94
Post	22 (73.3%)	24 (80.0%)		17 (56.7%)	20 (66.7%)	20 (66.7%)		29 (90.6%)	31 (91.2%)
Race
White	30 (100.0%)	30 (100.0%)	–	30 (100.0%)	27 (90.0%)	23 (88.5%)	0.17	30 (93.8%)	32 (97.0%)	0.54
Non-white	0 (0%)	0 (0%)		0 (0%)	3 (10.0%)	3 (11.5%)		2 (6.2%)	1 (3.0%)
OC use
Ever	10 (33.3%)	13 (43.3%)	0.43	10 (33.3%)	11 (36.7%)	10 (38.5%)	0.92	18 (56.2%)	20 (60.6%)	0.72
Never	20 (66.7%)	17 (56.7%)		20 (66.7%)	19 (63.3%)	16 (61.5%)		14 (43.8%)	13 (39.4%)
Parity
Nulliparous	4 (13.3%)	6 (20.7%)	0.45	5 (16.7%)	9 (30.0%)	7 (26.9%)	0.46	3 (9.4%)	3 (8.8%)	0.94
Parous	26 (86.7%)	23 (79.3%)		25 (83.3%)	21 (70.0%)	19 (73.1%)		29 (90.6%)	31 (91.2%)
Year of specimen collection
2001–2002	10 (33.3%)	8 (26.7%)	0.4	8 (26.7%)	10 (33.3%)	3 (10.0%)	0.19	10 (31.2%)	11 (32.4%)	0.91
2003–2005	8 (26.7%)	13 (43.3%)		13 (43.3%)	11 (36.7%)	12 (40.0%)		15 (46.9%)	17 (50.0%)
2006–2010	12 (40.0%)	9 (30.0%)		9 (30.0%)	9 (30.0%)	15 (50.0%)		7 (21.9%)	6 (17.6%)
Length of storage
<5.4 years	13 (43.3%)	9 (30.0%)	0.07	11 (36.7%)	10 (33.3%)	17 (56.7%)	0.25	8 (25.0%)	8 (23.5%)	0.84
5.44–7.6 years	84(13.3%)	12 (40.0%)		9 (30.0%)	10 (33.3%)	9 (30.0%)		11 (34.4%)	14 (41.2%)
>7.6 years	13 (43.3%)	9 (30.0%)		10 (33.3%)	10 (33.3%)	4 (13.3%)		13 (40.6%)	12 (35.3%)