Table 3.
Comparisons of model fit for models containing age and menopausal markers (anti-Müllerian hormone (AMH), antral follicle count (AFC), and follicle stimulating hormone (FSH). Odds ratios (95% confidence intervals) for age, AMH, AFC, and FSH shown; bold type indicates statistical significance at p<0.05.*
| Odds ratios (95% confidence intervals) |
C-statistic | Akaike Information Criterion (AIC) |
Likelihood ratio test vs. models with age alone |
Likelihood ratio test vs. models with age and AMH |
|
|---|---|---|---|---|---|
| Age alone | 0.83 | 254.9 | - | - | |
| Age (years) | 7.4 (4.1, 13.6) | ||||
| Age and AMH | 0.91 | 199.4 | <0.001 | ||
| Age (years) | 4.1 (2.1, 7.9) | ||||
| AMH (ng/dl) | 0.13 (0.05, 0.34) | ||||
| Age and AFC | 0.84 | 250.1 | 0.009 | ||
| Age (years) | 6.5 (3.5, 12.0) | ||||
| AFC (number) | 0.33 (0.13, 8.2) | ||||
| Age and FSH | 0.85 | 239.4 | <0.001 | 0.077 | |
| Age (years) | 6.1 (3.3, 11.3) | ||||
| FSH (IU/L) | 0.79 (0.18, 3.6) | ||||
| Age, AMH, FSH | 0.92 | 198.3 | <0.001 | ||
| Age (years) | 3.9 (2.0, 7.8) | ||||
| AMH (ng/dl) | 0.18 (0.07, 0.43) | ||||
| FSH (IU/L) | 0.47 (0.10, 2.3) | ||||
| Age, FSH, AFC | 0.86 | 238.5 | <0.001 | 0.275 | |
| Age (years) | 5.7 (3.0, 10.6) | ||||
| AFC (number) | 0.47 (0.19, 1.2) | ||||
| FSH (IU/L) | 0.77 (0.17, 3.4) | ||||
| Age, AMH, AFC | 0.91 | 200.2 | <0.001 | ||
| Age (years) | 4.1 (2.1, 8.0) | ||||
| AMH (ng/dl) | 0.12 (0.04, 0.31) | ||||
| AFC (number) | 2.0 (0.57, 6.9) | ||||
| Age, AMH, FSH, AFC | 0.91 | 198.3 | <0.001 | 0.070 | |
| Age (years) | 3.9 (2.0, 7.8) | ||||
| AMH (ng/dl) | 0.15 (0.06, 0.39) | ||||
| FSH (IU/L) | 0.44 (0.09, 2.2) | ||||
| AFC (number) | 2.4 (0.69, 8.6) |
For estimation of odds ratios, model assumptions are shown for women aged 45–49 years, with AFC 0–10 follicles, FSH 0–13.9 IU/L, and AMH 0.09–0.50 ng/dl.