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. 2017 Jul 20;12(7):e0181535. doi: 10.1371/journal.pone.0181535

Fig 1. Effect of Dox, RSV-Dox and Dox-RSV on %EF, %FS was measured by echocardiography. RSV treatment prevented Dox induced deterioration of cardiac function.

Fig 1

(A) Graphical representation of time points for treatment protocol. (B). Representative M-mode images from different groups. (C). % Ejection fraction (%EF). (D). % Fractional shortening (%FS). Dox treatment for 2 weeks significantly decreased both %EF and %FS, RSV treatment along with Dox or after 2 weeks of Dox supplementation mitigated Dox induced deterioration of cardiac function. Data are mean ± SD, *P < 0.05, significantly different from respective control group, #P <0.05, compared to respective Dox group.