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. 2017 Jul 20;12(7):e0181535. doi: 10.1371/journal.pone.0181535

Fig 4. Resveratrol treatment mitigates Dox induced cardiac fibrosis.

Fig 4

(A) Masson’s trichrome staining: Photomicrographs of rat myocardial sections (X 200): Control group showed fine collagen fibers (arrows) among muscle fibers. Dox group showed dense collagen fibers (arrows) among thin muscle fibers. RSV-Dox group showed fine collagen fibers (arrows) among muscle fibers. In Dox-RSV group lesser amount of dense collagen fibers (arrows) among muscle fibers were detected. (B) Quantitative analysis (percent area) of collagen fibers. Data are mean ± SD. *P < 0.05, significantly different from respective control group, #P < 0.05, significantly different from respective Dox group, $P < 0.05, significantly different from respective Dox-RSV group.