Table 1. Characteristics of the participants according to CAD status.
| Non-CAD N = 492 |
CAD N = 220 |
P | |
|---|---|---|---|
| Male (%) | 205 (41.7%) | 141 (64.1%) | <0.001 |
| Age (years) | 51.11(±13.43) | 63.51(±10.46) | 0.004 |
| Diabetes mellitus (%) | 61 (12.4%) | 110 (50%) | <0.001 |
| Hypertension (%) | 140 (28.5%) | 175 (79.5%) | <0.001 |
| Dyslipidemia (%) | 78 (15.9%) | 112 (50.9%) | <0.001 |
| Smoking | 70 (14.3%) | 59 (26.8%) | <0.001 |
| Lipid-lowering medication (%) | 39 (8%) | 166 (77.9%) | <0.001 |
| Anthropometric | |||
| Waist circumference | 90.4 (±13.8) | 98.54 (±11.8) | <0.001 |
| BMI (kg/m2) | 27.3 (±5.9) | 27.4 (± 4.7) | 0.831 |
| Obesity (BMI ≥ 30 kg/m2) | 143 (29.4%) | 50 (22.9%) | 0.077 |
| Genotype (%) | 0.762 | ||
| ε2/ε2 | 5 (1%) | 2 (0.9%) | |
| ε2/ε3 | 53 (10.8%) | 27 (12.3%) | |
| ε2/ε4 | 19 (3.9%) | 5 (2.3%) | |
| ε3/ε3 | 241 (49%) | 100 (45.4%) | |
| ε3/ε4 | 150 (30.5%) | 76 (34.6%) | |
| ε4/ε4 | 24 (4.9%) | 10 (4.5%) | |
| Allele frequency | 0.972 | ||
| ε2 | 8.3 | 8.2 | |
| ε3 | 69.6 | 68.9 | |
| ε4 | 22.1 | 22.9 |
Data are presented as means ± SD or number (percentage)
The Fisher’s exact test was used to compare genotype distribution and the chi-squared test to compare allele frequencies and other proportions, among CAD and non-CAD groups.