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(A) PD-L1-positive cases showed higher expression of IL-38 than PD-L1-negative cases (Wilcoxon rank-sum test: P < 0.0001). (B) Representative images of (upper panel) PD-L1 staining and (lower panel) IL-38 staining in a (left panel) PD-L1-negative case and (right panel) PD-L1-positive case. IHC: immunohistochemistry, PD-L1: programmed cell death-ligand 1, IL-38: interleukin-38. Scale bar: 100 μm.
