Table 3. Characteristics of individual studies included in the meta-analysis of the PPARG Pro12Ala polymorphism and blood pressure.
First author | Year | Country | Ethnicity | Subpopulation | Genotypes | Number (n) | SBP | DBP | ||
---|---|---|---|---|---|---|---|---|---|---|
M | SD | M | SD | |||||||
Zhang AP | 2005 | China | Asian | All | Pro/Pro | 276 | 158.6 | 25.1 | 95.6 | 15.3 |
Pro/Ala | 13 | 132.3 | 16.7 | 91.3 | 12.5 | |||||
Shen D | 2005 | China | Asian | EH | Pro/Pro | 66 | 155.6 | 13.5 | 90.3 | 7.2 |
Pro/Ala+Ala/Ala | 4 | 159.3 | 15.8 | 91.7 | 7.6 | |||||
Gao L | 2010 | China | Asian | EH | Pro/Pro | 337 | 147.8 | 15.4 | 88.1 | 11.2 |
Pro/Ala+Ala/Ala | 8 | 150.8 | 21.3 | 88.3 | 11.1 | |||||
Control | Pro/Pro | 131 | 111.9 | 11.0 | 73.3 | 9.1 | ||||
Pro/Ala+Ala/Ala | 6 | 120.5 | 14.5 | 71.7 | 10.1 | |||||
Zhang XF δ | 2013 | China | Asian | EH | Pro/Pro | 125 | 155.6 | 11.6 | 92.1 | 11.9 |
Pro/Ala+Ala/Ala | 21 | 154.7 | 10.3 | 91.8 | 9.1 | |||||
Control | Pro/Pro | 101 | 117.5 | 10.2 | 74.9 | 8.4 | ||||
Pro/Ala | 11 | 115.0 | 15.9 | 74.6 | 9.3 | |||||
Zhang XF & | 2013 | China | Asian | EH | Pro/Pro | 137 | 153.7 | 15.4 | 94.1 | 9.8 |
Pro/Ala+Ala/Ala | 26 | 155.4 | 17.49 | 95.2 | 9.6 | |||||
Control | Pro/Pro | 158 | 123.7 | 10.2 | 75.4 | 7.5 | ||||
Pro/Ala | 20 | 126.4 | 7.0 | 76.7 | 7.1 | |||||
Grygiel-Górniak B | 2015 | Poland | Caucasian | EH | Pro/Pro | 101 | 158.2 | 15.0 | 96.8 | 11.4 |
Pro/Ala | 44 | 155.3 | 15.6 | 94.8 | 12.1 | |||||
Ala/Ala | 6 | 158.7 | 20.6 | 104.8 | 10.0 | |||||
Control | Pro/Pro | 84 | 122.3 | 10.0 | 77.8 | 6.9 | ||||
Pro/Ala | 32 | 119.0 | 12.0 | 76.1 | 6.7 | |||||
Ala/Ala | 4 | 117.5 | 10.7 | 79.0 | 5.6 |
δ, Hui subgroup
&, Chinese Han subgroup
EH, essential hypertension; SBP, systolic blood pressure; DBP, diastolic blood pressure; M, mean; SD, standard deviations