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. 2017 Jul 20;12(7):e0181644. doi: 10.1371/journal.pone.0181644

Table 3. Characteristics of individual studies included in the meta-analysis of the PPARG Pro12Ala polymorphism and blood pressure.

First author Year Country Ethnicity Subpopulation Genotypes Number (n) SBP DBP
M SD M SD
Zhang AP 2005 China Asian All Pro/Pro 276 158.6 25.1 95.6 15.3
Pro/Ala 13 132.3 16.7 91.3 12.5
Shen D 2005 China Asian EH Pro/Pro 66 155.6 13.5 90.3 7.2
Pro/Ala+Ala/Ala 4 159.3 15.8 91.7 7.6
Gao L 2010 China Asian EH Pro/Pro 337 147.8 15.4 88.1 11.2
Pro/Ala+Ala/Ala 8 150.8 21.3 88.3 11.1
Control Pro/Pro 131 111.9 11.0 73.3 9.1
Pro/Ala+Ala/Ala 6 120.5 14.5 71.7 10.1
Zhang XF δ 2013 China Asian EH Pro/Pro 125 155.6 11.6 92.1 11.9
Pro/Ala+Ala/Ala 21 154.7 10.3 91.8 9.1
Control Pro/Pro 101 117.5 10.2 74.9 8.4
Pro/Ala 11 115.0 15.9 74.6 9.3
Zhang XF & 2013 China Asian EH Pro/Pro 137 153.7 15.4 94.1 9.8
Pro/Ala+Ala/Ala 26 155.4 17.49 95.2 9.6
Control Pro/Pro 158 123.7 10.2 75.4 7.5
Pro/Ala 20 126.4 7.0 76.7 7.1
Grygiel-Górniak B 2015 Poland Caucasian EH Pro/Pro 101 158.2 15.0 96.8 11.4
Pro/Ala 44 155.3 15.6 94.8 12.1
Ala/Ala 6 158.7 20.6 104.8 10.0
Control Pro/Pro 84 122.3 10.0 77.8 6.9
Pro/Ala 32 119.0 12.0 76.1 6.7
Ala/Ala 4 117.5 10.7 79.0 5.6

δ, Hui subgroup

&, Chinese Han subgroup

EH, essential hypertension; SBP, systolic blood pressure; DBP, diastolic blood pressure; M, mean; SD, standard deviations