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. 2016 Oct 7;14(6):761–778. doi: 10.1080/15476286.2016.1243649

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Figure 1. — PTMs and snRNP biogenesis. A model showing known modifications of proteins involved in snRNP biogenesis, including the snRNA export pathway. Enzymes that modify these proteins are shown. Phosphorylated, methylated, ubiquitinated and sumoylated proteins are indicated. Processes marked by question marks indicate that there is no information on how PTMs affect localization or interaction; or where the PTM is known, but the enzyme(s) responsible for the modification are not known. Proteins that are modified, such as TGS1, but the functional consequence of this modification and the modifying enzymes are unknown, are indicated in the figure but lack denoted modification. Also not shown in the model are proteins with combinations of PTMs. (P = Phosphorylation; Me = Methylation; So = Sumoylation; Ub = Ubiquitination).