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Interaction of PRC2 and substrate. (A) Interaction of human PRC2 with H3K27M peptide. (B) Interaction of human PRC2 with JARID2K116me3 peptide. (C) Interaction of human PRC2 with SAH. (D) Interaction of fungal PRC2 with H3K27me3 peptide. The specific interactions between PRC2 and peptide or SAH are indicated by blue lines. The interactions were analyzed by LigPlus and graphed using PyMol.
