Table 2. Structural parameters obtained with the Cirrus HD optical coherence tomography device in healthy controls and subjects with Alzheimer's disease.
| Structural parameters | Healthy subjetcs | Alzheimer patients | P |
|---|---|---|---|
| Macular thickness | |||
| Fovea | 262.03 (18.31) | 263.12 (23.53) | 0.530 |
| Inner superior sector | 331.65 (13.06) | 310.44 (27.58) | 0.010 |
| Inner nasal sector | 333.42 (13.33) | 317.19 (21.44) | 0.010 |
| Inner inferior sector | 330.97 (12.34) | 307.75 (31.87) | <0.001* |
| Inner temporal sector | 319.55 (13.19) | 305.94 (20.33) | 0.030 |
| Outer superior sector | 288.23 (9.34) | 269.63 (21.57) | <0.001* |
| Outer nasal sector | 306.39 (11.14) | 285.88 (19.28) | <0.001* |
| Outer inferior sector | 281.13 (9.66) | 258.69 (35.62) | 0.010 |
| Outer temporal sector | 274.00 (10.10) | 255.69 (33.06) | <0.001* |
| RNFL thickness | |||
| Average | 97.61 (7.13) | 91.00 (11.23) | <0.001* |
| Superior quadrant | 119.29 (10.53) | 110.06 (20.71) | <0.001* |
| Nasal quadrant | 74.03 (13.26) | 71.44 (14.40) | 0.780 |
| Inferior quadrant | 131.06 (12.51) | 120.00 (17.24) | 0.180 |
| Temporal quadrant | 65.87 (9.04) | 62.12 (9.12) | 0.720 |
Abbreviation: RNFL, retinal nerve fiber layer.
Results are reported as mean (SD). Results in bold letters indicate statistical significance (P<0.050). Asterisk indicates a significant difference by Student’s t test after Bonferroni correction for multiple tests (P≤0.006 for macular measurements; P≤0.010 for RNFL measurements).