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. 2017 Mar 10;31(7):1034–1041. doi: 10.1038/eye.2017.23

Table 3. Correlation between structural parameters (macular and retinal nerve fiber layer thickness) and contrast sensitivity vision (CSV) evaluated with Pelli-Robson and CSV-1000E tests in patients with Alzheimer's disease.

  CSV-1000E TEST
Pelli Robson
  6 CPD P-value 9 CPD P-value 12 CPD P-value 18 CPD P-value R P-value
Macular thickness
 Fovea 0.043 0.770 0.19 0.900 0.45 0.760 0.14 0.330 −0.02 0.881
 Inner superior sector 0.43 0.030 0.35 0.010 0.44 0.020 0.43 0.030 0.45 <0.001*
 Inner nasal sector 0.48 0.010 0.37 0.010 0.44 0.020 0.43 0.040 0.48 <0.001*
 Inner inferior sector 0.34 0.020 0.28 0.050 0.40 <0.001* 0.38 0.010 0.47 <0.001*
 Inner temporal sector 0.42 0.030 0.23 0.110 0.36 0.010 0.44 <0.001* 0.43 <0.001*
 Outer superior sector 0.50 <0.001* 0.36 0.010 0.57 <0.001* 0.50 <0.001* 0.65 <0.001*
 Outer nasal sector 0.50 <0.001* 0.50 <0.001* 0.49 <0.001* 0.50 <0.001* 0.58 <0.001*
 Outer inferior sector 0.17 0.240 0.27 0.050 0.38 <0.001* 0.32 0.030 0.38 <0.001*
 Outer temporal sector 0.47 <0.001* 0.22 0.120 0.50 <0.001* 0.39 <0.001* 0.66 <0.001*
 Average thickness 0.43 0.090 0.21 0.420 0.56 0.030 0.53 0.050 0.63 <0.001*
 Macular volume 0.48 0.050 0.34 0.150 0.30 0.240 0.27 0.320 0.54 0.010
 
Rnfl thickness
 Average 0.41 0.040 0.33 0.020 0.43 <0.001* 0.40 <0.001* 0.46 <0.001*
 Superior quadrant 0.31 0.030 0.23 0.040 0.46 <0.001* 0.41 <0.001* 0.46 <0.001*
 Nasal quadrant 0.37 0.010* 0.19 0.200 0.20 0.190 0.11 0.440 0.37 0.010*
 Inferior quadrant 0.22 0.140 0.11 0.440 0.23 0.120 0.23 0.110 0.22 0.140
 Temporal quadrant 0.23 0.110 0.35 0.010* 0.26 0.740 0.35 0.010* 0.12 0.410

Abbreviations: CSV, contrast sensitivity vision; RNFL, retinal nerve fiber layer.

Data in bold correspond to statistically significant correlations (P-value <0.05). Asterisk indicates a significant difference by Pearson’s test after Bonferroni's correction for multiple tests (P≤0.0045 for macular thickness; P≤0.010 for RNFL thickness).