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INT-767 has direct effects in cultured human podocytes. The expression of TNF-α, TLR2, and TLR4 is increased in the aging serum-conditioned human podocytes, but this effect is abolished by treatment with INT-767. Error bars represent S.D. n = 3. *, p < 0.05 versus old; **, p < 0.05 versus old. INT, INT-767-treated.
