FIG. 3.

(Color online) Competition between RanGTP and cargo to bind importin: (A) Schematic of the two competing reactions: (B) Reaction flux for importin-RanGTP formation ${\stackrel{\sim }{\mathrm{\Phi }}}_4^{+}~k_4^{+}[\mathit{RanGTP}]$ and (C) that for importin-cargo formation ${\stackrel{\sim }{\mathrm{\Phi }}}_7^{-}~k_7^{-}{[C]}_{nu}$. Fluxes are scaled by [Im]_nu (see text). Parameters as in FIG. 2