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. Author manuscript; available in PMC: 2017 Nov 7.
Published in final edited form as: Mol Pharm. 2016 Oct 10;13(11):3747–3755. doi: 10.1021/acs.molpharmaceut.6b00538

Fig. 6. Dynamic PET scans.

Fig. 6

25 minute dynamic PET scans were acquired on anesthetized mice containing xenografted EGFRhigh tumors. The average signal within ~15 mm3 regions, guided by an anatomical CT scan, is presented. Data were fit assuming exponential kinetics. The clearance half-time within the heart (predominantly blood pool) was t1/2 = 3.2 ± 1.0 min (n=2 mice).