Table 1.
Anthropometric parameters and biochemical indexes among study subjects (n = 245).
| Variables | NGT (n = 63) | I-IGT (n = 37) | I-IFG (n = 30) | CGI (n = 37) | T2DM (n = 78) | P |
|---|---|---|---|---|---|---|
| Male/Female (n) | 36/27 | 20/17 | 15/15 | 18/19 | 39/39 | 0.902 |
| Age (years) | 53.7 ± 11.7 | 54.0 ± 12.8 | 52.9 ± 13.3 | 54.0 ± 8.9 | 55.7 ± 12.9 | 0.870 |
| BMI (kg/m2) | 23.5 ± 2.7 | 24.1 ± 3.0 | 23.8 ± 2.3 | 24.3 ± 2.3 | 24.3 ± 3.1 | 0.470 |
| SBP (mmHg) | 123.92 ± 15.62 | 126.89 ± 15.81 | 130.70 ± 16.90 | 131.65 ± 21.37 | 129.35 ± 18.20 | 0.183 |
| DBP (mmHg) | 74.68 ± 9.68 | 76.43 ± 10.53 | 73.77 ± 11.99 | 77.68 ± 12.78 | 77.19 ± 9.84 | 0.381 |
| FPG (mmol/L)§ | 5.25 (4.84–5.56) | 5.47 (5.04–5.71) | 6.38‡ (6.20–6.60) | 6.38‡ (6.27–6.68) | 7.11‡ (6.33–7.51) | <0.001 |
| 2hPG (mmol/L)§ | 6.23 (5.55–6.88) | 9.31‡ (8.19–10.01) | 6.55 (5.84–7.20) | 9.55‡ (8.94–10.22) | 13.78‡ (10.70–16.03) | <0.001 |
| FINS (μU/mL)§ | 6.60 (5.02–10.09) | 8.78 (5.89–11.68) | 9.01 (6.01–10.79) | 6.56 (5.66–8.53) | 10.13‡ (6.77–12.38) | 0.001 |
| 2hINS (μU/mL)§ | 56.86 (35.99–92.40) | 102.20‡ (56.65–143.40) | 65.51 (33.58–88.61) | 69.23 (47.22–94.28) | 76.78† (51.77–111.20) | <0.001 |
| HOMA-IR§ | 1.53 (1.17–2.34) | 2.18 (1.30–2.83) | 2.57‡ (1.74–2.99) | 1.92† (1.63–2.45) | 3.10‡ (2.12–4.01) | <0.001 |
| HOMA-%B§ | 80.00 (55.44–112.20) | 92.89 (65.95–127.06) | 61.52‡ (39.68–81.39) | 43.85‡ (38.02–58.73) | 60.41‡ (36.86–84.04) | <0.001 |
Data are mean ± SD or median (interquartile range). §Log transformed before analysis. CGI, combined glucose intolerance; DBP, diastolic blood pressure; FINS, fasting serum insulin concentration; FPG, fasting plasma glucose concentration; HOMA-%B, homeostasis model assessment of insulin secretion; HOMA-IR, homeostasis model assessment of insulin resistance; I-IFG, isolated-impaired fasting glucose; I-IGT, isolated-impaired glucose tolerance; NGT, normal glucose tolerance; 2hPG, 2-h plasma glucose concentration; SBP, systolic blood pressure; T2DM, type 2 diabetes mellitus; 2hINS, 2-h serum insulin concentration; † P < 0.05, compared with NGT; ‡ P < 0.01, compared with NGT.