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. 2017 Jul 20;7:6015. doi: 10.1038/s41598-017-06471-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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PNS or Rb1 and Rd combination preserved retinal function in bright light-exposed mice. BALB/c mice were treated with vehicle, PNS at 200 mg/kg bw, or natural combination of Rb1 and Rd 30 min before bright light exposure. Retinal function was examined 10 d after bright light exposure. Scotopic ERGs were recorded and amplitudes of a-wave (A) and b-wave (B) were plotted. Data were expressed as mean ± S.E.M (n = 4–5 per group). *Compared to that from No light, p < 0.05; ^#PNS treatment was compared to that from Vehicle, p < 0.05; ^&Combination treatment of Rb1 and Rd was compared to that from Vehicle, p < 0.05.