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dTTP biosynthesis pathways and enzymes. Processes present in Mycobacteria are shown in black. Most organisms encode for additional de novo and salvage pathways that are shown in grey. Abbreviations: Dcd – dCTP deaminase, Dut – dUTPase, Dctd – dCMP deaminase, Dcd:dut – bifunctional dCTP deaminase: dUTPase, Nrd – Nucleoside diphosphate reductase, Ndk – Nucleoside diphosphate kinase, Tmpk – dTMP kinase, Tk – Thymidine kinase, ThyA,ThyX – thymidylate synthases.
