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. 2017 Jul 20;7:6060. doi: 10.1038/s41598-017-06177-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Titer histograms for 2009 H1N1, showing fit results for mixture models with different numbers of normal components (top to bottom; the label to the left of the y‐axis is the number of mixture components) and grouped by collection sites. Histograms are weighted to adjust for age and gender according to the Vietnam national housing census in 2009 for each of the four collection sites. The blue lines in each panel are the normalized probability density functions of the component distributions with darker colors used for increasing μ. The black lines show the full mixture distribution density, and the black dots are the estimated cumulative distribution of the mixture models at 7.0 (titer of 1280). The numbers in the upper right corner of each panel are the BIC scores of the model fits. The fractions of individuals with titers below the detection limit of 20 and above 1280 that were out of the plotting ranges were given next to their respective bars.