Table 2.

Impacts of adverse events and tumour response on EQ-5D scores

	Separate analyses			Simultaneous analysis
	Estimate	95% CI	p	Estimate	95% CI	p
Adverse event (per one-grade increase)
Nausea	−0.050	−0.065 to −0.035	<0.001	−0.008	−0.027 to 0.011	0.421
Vomiting	−0.053	−0.070 to −0.036	<0.001	−0.018	−0.038 to 0.001	0.061
Diarrhoea	−0.013	−0.030 to 0.005	0.167	0.009	−0.008 to 0.026	0.283
Fatigue	−0.057	−0.070 to −0.043	<0.001	−0.034	−0.049 to −0.018	<0.001
Anorexia	−0.053	−0.065 to −0.042	<0.001	−0.032	−0.047 to −0.017	<0.001
Response (per one-level improvement)
	0.059	0.045 to 0.073	<0.001	-	-	-

EQ-5D, EuroQol-5D-3L.