Table 2.
Incidence of multiple primaries over all cancer sites in the literature
| Number of patients evaluated | Geographic region | Frequency of multiple primaries | Mean follow-up (years) |
Definition used for multiple primary (SEER/IACR/IARC) |
Reference |
| 19 252 | Italy | 2.4% | 2.5 | IACR | 5 |
| 1 015 564 men | USA | 15.8% | NA | SEER |
6
|
| 951 022 women | 14.4% | IACR | |||
| 17.2% | SEER | ||||
| 14.55 | IACR | ||||
| 334 168 | Victoria, Australia | 4.3% | 5 | IACR | 8 |
| 7.7% | 10 | ||||
| 12.4% | 20 | ||||
| 2 919 023 | 22 European countries | 6.3% | NA | IACR | 7 |
| 57 393 | West of Scotland | 5% | 5 | IACR | 4 |
| 938 | Netherlands | 7% | NA | NA | 17 |
| 1873 | USA | 7.2% | 5 | SEER | 11 |
| 11.4% | 10 | ||||
| 13.3% | 15 | ||||
| 14.8% | 20 | ||||
| 17.2% | >20 | ||||
| 1953 | USA | 2.15% | 20 | NA | 14 |
| 1 635 060 | Italy | 6.3% | 14 | IACR | 16 |
| 82 671 | Switzerland | 8.17% | 6.6 | IACR | Authors of this publication |
IACR, International Association of Cancer Registries; IARC, International Agency for Research on Cancer; SEER, Surveillance Epidemiology and End Results.