Table 6.

Maximum toxicity per patient during adjuvant S-1 monotherapy (n=5)

Adverse event	NCI CTC grade
Haematologic	1	2	3	4	All, %	3/4, %
Leucopenia	1	1	0	0	40	0
Neutropaenia	0	2	1	0	60	20
Anaemia	3	1	1	0	100	20
Thrombocytopaenia	2	0	0	0	40	0
Non-haematologic
Anorexia	1	2	0	0	60	0
Alopecia	2	0	0	0	40	0
Constipation	2	0	0	0	40	0
Diarrhoea	2	0	0	0	40	0
Dysgeusia	2	0	0	0	40	0
Dysphagia	2	0	0	0	40	0
Fatigue	4	0	0	0	80	0
Febrile neutropaenia	-	-	0	0	0	0
Nausea/vomiting	1	0	0	0	20	0
Palmar-plantar erythrodysesthesia syndrome	0	1	0	0	20	0
Peripheral sensory neuropathy	1	0	0	0	20	0
Skin hyperpigmentation	2	0	0	0	40	0
Watering eyes	1	0	0	0	20	0

NCI CTC, National Cancer Institute Common Toxicity Criteria.