Table 2.
Variable | Pemetrexed arm (n=141) | Gefitinib arm (n=145) |
Haematological | ||
Anaemia | 111 (78.7%) | 77 (53.1%) |
Neutropaenia | 53 (37.6%) | 4 (2.8%) |
Thrombocytopaenia | 57 (40.4%) | 10 (6.9%) |
Biochemical | ||
Raised SGOT | 57 (40.4%) | 77 (53.1%) |
Raised SGPT | 72 (51.1%) | 79 (54.5%) |
Clinical | ||
Skin rash | 40 (28.4%) | 101 (69.7%) |
Loose motions | 39 (27.7%) | 67 (46.2%) |
Vomiting | 34 (24.1%) | 19 (13.1%) |
Febrile neutropaenia | 12 (8.5%) | 1 (0.7%) |
SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamic aspartate aminotransferase.