Table 1.

Sex, Age, Smoking History, and Clinical Characteristics of the Analyzed Susceptible and Resistant Subcohorts

	Emphysema Susceptible	Emphysema Resistant	P Value*
Number of subjects sequenced	64	65
Females, %	43.8	47.7	0.67
Age at PFT, yr, median (IQR)	61 (57–65)	63 (60–66)	0.01
Smoking history, pack-years, mean (IQR)	54.4 (35.6–61.5)	48.5 (30.0–60.0)	0.25
FEV1, % predicted, mean (IQR)	25.3 (19.8–30.0)	98.0 (89.0–104.0)	7.63 × 10−29
F-950, mean (IQR)	0.269 (0.172–0.351)	0.004 (0.002–0.006)	2.00 × 10−24

Definition of abbreviations: F-950 = Hounsfield units value less than −950; IQR = interquartile range; PFT = pulmonary function testing.

^*Two-tailed Student’s t test.