Table 2. Average diffusion constants obtained from single molecule tracking data (mean±s.d.).

Ligand	D (μm2 s−1)
DN (primarily binary complex)	0.113±0.002*
KFR (primarily ternary complex)	0.086±0.001*
IL-4	0.091±0.001*
RGA	0.088±0.001*
IL-13	0.099±0.001*
IL-4Rα (w/o ligand)	0.119±0.010†
IL-4Rα (w/ KFR)	0.107±0.002†
IL-13Rα1 (w/o ligand)	0.140±0.012†
IL-13Rα1 (w/KFR)	0.108±0.001†
IL-4Rα/IL-13Rα1 dimers (ligand induced)	0.087±0.003‡

^*Obtained with DY647-labelled ligands bound to the endogenous receptor.

^†Mean values determined in cells co-expressing IL-4Rα and IL-13Rα1 without ligand and after addition of KFR.

^‡Mean values from ^DY647IL-4Rα/^TMRIL-13Rα1 co-trajectories in presence of either IL-4, IL-13 or KFR.