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. 2017 Jul 17;8:16092. doi: 10.1038/ncomms16092

Figure 4. Pharmacokinetic study in rats.

Figure 4

(a) Concentration of peptides in rat plasma at indicated time points after i.v. administration of 0.5 mg kg−1 tagged bicyclic peptides, 0.3 mg kg−1 UK18 or 0.25 mg kg−1 tag (n=3). s.d.’s are indicated. (b) Analysis of peptides in rat blood samples by RP-HPLC using a fluorescence detector.