Table 2. Description of compared IRPs.
| IRP | 1000G | HRC | EGCUT | EGCUT + 1000G | 1000G + EGCUT |
|---|---|---|---|---|---|
| Description | 26 cohorts worldwide | 20 cohorts of mostly European ancestry | Estonian diversity panel | 1+26 cohorts worldwide | 26+1 cohorts worldwide |
| Average sequencing coverage | 7.4 × | 4–8 × | 29.8 × | 29.8 × | 7.4 × |
| MAC filter | MAC≥1 | MAC≥5 | MAC≥3 | MAC≥1 | MAC≥1 |
| No of haplotypes | 5008 | 64976 | 4488 | 9496 | 9496 |
| No of autosomal SNVs | 81 027 987 | 39 235 157 | 16 536 512 | 16 536 512 | 81 027 987 |
Abbreviations: HRC, Haplotype Reference Consortium; IRP, imputation reference panel; SNV, single-nucleotide variant.