Table 1. Study and participants characteristics by cohort in the CHANCES consortium of middle-aged and older adults.
EPIC Elderly |
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Characteristics | Denmark | Greece | Netherlands | Spain | Germany (ESTHER) | Northern Ireland (PRIME Belfast) | Norway (Tromsø) | |||||||||||||||||||||
Recruitment year, range | 1993–1997 |
1994–1999 |
1993–1997 |
1992–1996 |
2000–2003 |
1991–1994 |
1994–1995 |
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Age at entry, years (s.d.) | 62.5 | 1.5 | 66.9 | 4.4 | 64.3 | 2.7 | 62.5 | 1.7 | 61.9 | 6.6 | 54.2 | 2.8 | 59.4 | 6.9 | ||||||||||||||
Sex | ||||||||||||||||||||||||||||
Men, n (%) | 5072 | 46.4 | 2882 | 40.1 | 210 | 4.9 | 1949 | 42.5 | 3849 | 44.9 | 1944 | 100 | 2762 | 46.7 | ||||||||||||||
Women, n (%) | 5853 | 53.6 | 4299 | 59.9 | 4085 | 95.1 | 2635 | 57.5 | 4728 | 55.1 | 0 | 0 | 3151 | 53.3 | ||||||||||||||
Education | ||||||||||||||||||||||||||||
Low, n (%) | 4193 | 38.4 | 6539 | 91.1 | 1303 | 30.3 | 3927 | 85.7 | 6197 | 72.3 | 15 | 0.8 | 3033 | 51.3 | ||||||||||||||
Medium, n (%) | 4889 | 44.8 | 398 | 5.5 | 2451 | 57.1 | 320 | 7.0 | 1757 | 20.5 | 1677 | 86.3 | 1726 | 29.2 | ||||||||||||||
High, n (%) | 1827 | 16.7 | 220 | 3.1 | 521 | 12.1 | 287 | 6.3 | 415 | 4.8 | 252 | 13.0 | 1118 | 18.9 | ||||||||||||||
Unknown, n (%) | 16 | 0.2 | 24 | 0.3 | 20 | 0.5 | 50 | 1.1 | 208 | 2.4 | 0 | 0.0 | 36 | 0.6 | ||||||||||||||
BMI at baseline, kg m−2 (s.d.) | 26.2 | 3.9 | 29.3 | 4.3 | 25.8 | 3.9 | 29.5 | 4.0 | 27.6 | 4.2 | 26.1 | 3.2 | 26.1 | 3.7 | ||||||||||||||
Underweight, n (%) | 62 | 0.6 | 19 | 0.3 | 46 | 1.1 | 4 | 0.1 | 33 | 0.4 | 8 | 0.4 | 44 | 0.7 | ||||||||||||||
Normal weight, n (%) | 4421 | 40.5 | 1114 | 15.5 | 1947 | 45.3 | 493 | 10.8 | 2323 | 27.1 | 723 | 37.2 | 2377 | 40.2 | ||||||||||||||
Overweight, n (%) | 4861 | 44.5 | 3125 | 43.5 | 1745 | 40.6 | 2167 | 47.3 | 4064 | 47.4 | 998 | 51.3 | 2661 | 45.0 | ||||||||||||||
Obese, n (%) | 1581 | 14.5 | 2923 | 40.7 | 557 | 13.0 | 1920 | 41.9 | 2157 | 25.2 | 215 | 11.1 | 831 | 14.1 | ||||||||||||||
WC at baseline, cm (s.d.) | 89.1 | 12.4 | 95.9 | 11.4 | 84.2 | 10.3 | 97.1 | 10.7 | – | – | 90.9 | 9.1 | 90.1 | 10.9 | ||||||||||||||
HC at baseline, cm (s.d.) | 101.2 | 7.8 | 106.3 | 9.1 | 103.8 | 8.3 | 107.9 | 8.5 | – | – | 96.8 | 6.4 | 103.5 | 7.3 | ||||||||||||||
WHR at baseline, ratio (s.d.) | 0.88 | 0.10 | 0.90 | 0.09 | 0.81 | 0.07 | 0.90 | 0.08 | – | – | 0.94 | 0.05 | 0.87 | 0.08 | ||||||||||||||
Height at baseline, cm (s.d.) | 168.8 | 8.8 | 158.2 | 8.7 | 163.8 | 6.5 | 159.5 | 8.6 | 167.3 | 8.4 | 174.2 | 6.8 | 168.2 | 9.4 | ||||||||||||||
Vigorous physical activity | ||||||||||||||||||||||||||||
No, n (%) | 1752 | 16.0 | 5566 | 77.5 | 1669 | 38.9 | 4311 | 94 | 4853 | 56.6 | 1689 | 86.9 | 3528 | 59.7 | ||||||||||||||
Yes, n (%) | 5135 | 47.0 | 1506 | 21.0 | 2480 | 57.7 | 242 | 5.3 | 3704 | 43.2 | 255 | 13.1 | 2324 | 39.3 | ||||||||||||||
Unknown, n (%) | 4038 | 37.0 | 109 | 1.5 | 146 | 3.4 | 31 | 0.7 | 20 | 0.2 | 0 | 0.0 | 61 | 1.0 | ||||||||||||||
Alcohol intake, g per day (s.d.) | 19.0 | 19.8 | 7.5 | 15.4 | 7.8 | 11.9 | 13.0 | 22.2 | 6.8 | 9.4 | 20.3 | 30.4 | 3.6 | 5.1 | ||||||||||||||
Smoking status | ||||||||||||||||||||||||||||
Never daily smoker, n (%) | 3625 | 33.2 | 4891 | 68.1 | 2052 | 47.8 | 3109 | 67.8 | 4191 | 48.9 | 792 | 40.7 | 1950 | 33.0 | ||||||||||||||
Former daily smoker, n (%) | 4078 | 37.3 | 1285 | 17.9 | 1532 | 35.7 | 732 | 16.0 | 2772 | 32.3 | 637 | 32.8 | 2127 | 36.0 | ||||||||||||||
Current daily smoker, n (%) | 3201 | 29.3 | 805 | 11.2 | 694 | 16.2 | 740 | 16.1 | 1389 | 16.2 | 491 | 25.3 | 1831 | 30.9 | ||||||||||||||
Unknown, n (%) | 21 | 0.2 | 200 | 2.8 | 17 | 0.4 | 3 | 0.1 | 255 | 2.6 | 24 | 1.2 | 5 | 0.1 | ||||||||||||||
Median follow-up time, years | 11.9 | 11.5 | 13.2 | 13.4 | 10.5 | 18.0 | 15.9 | |||||||||||||||||||||
N cancers cases | ||||||||||||||||||||||||||||
N all obesity-relateda | 465 | 127 | 250 | 164 | 352 | 56 | 242 | |||||||||||||||||||||
N breast cancer (age>50 years, women only) | 193 | 22 | 109 | 42 | 125 | – | 64 | |||||||||||||||||||||
N colorectal cancer | 141 | 39 | 80 | 66 | 111 | 41 | 113 | |||||||||||||||||||||
N other obesity-relatedb | 131 | 66 | 61 | 56 | 116 | 15 | 65 |
Abbreviations: BMI=body mass index; HC=hip circumference; WC=waist circumference; WHR=waist-to-hip ratio.
Note: all values are means, except when stated otherwise.
First primary cancers of the breast (postmenopausal), colorectum, lower oesophagus, cardia stomach, liver, gallbladder, pancreas, endometrium, ovary, and kidney.
Same as all obesity-related cancers but excluding first primary cancers of the breast and of the colorectum.