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. 2017 Apr 25;116(11):1425–1435. doi: 10.1038/bjc.2017.116

Figure 1.

Figure 1

GLI1 expression correlates with VEGFR2 in TNBC patients. (A) Left, pie chart representing the percentage of samples included in the TMA that show immunoreactive score (IS) equal to 0, 1<IS<3 and IS>3 for VEGFR2 expression. Right, immunoistochemical images representing VEGFR2 negative (IS=0) or -positive tumours with moderate (1<IS<3) and high (IS>3) expression levels, respectively. Endothelial cells positivity represents internal control (× 20 magnification). The red arrows indicate representative highly VEGFR2 positive signal. (B) Left, pie chart representing the percentage of samples included in the TMA that show IS equal to 0, 1<IS<3 and IS>3 for GLI1 expression, respectively. Right, immunoistochemical images representing GLI1-negative (IS=0) or -positive tumours with moderate (1<IS<3) or high (IS>3) expression levels, respectively (× 20 magnification). The red arrows indicate representative highly GLI1 positive signal.