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. 2017 May 29;38(6):764–781. doi: 10.1038/aps.2017.42

Figure 13.

Figure 13

(A) Chemical structure of the conjugated polymer. (B) Schematic of lipase-sensitive conjugated polymer nanocarrier for orlistat delivery via oral gavage: orlistat release triggered by lipase, deactivation of lipase and inhibition of fat digestion, and negative feedback to control the release of the enzyme inhibitor. Reproduced with permission from Ref 122.