Figure 5.

Psoralidin inhibits CTPE xenografts tumour growth in nude mice. CTPE cells in a 50-μl (final volume) of phosphate-buffered saline and Matrigel (1 : 1) were subcutaneously injected into separate flanks of mice. Mice received vehicle (sesame oil; circles) or Pso (20 mg kg⁻¹ Bw; squares) orally for 5 days per week up to 5 weeks. Tumour volumes (mm³) (upper panel) and mouse body weight (lower panel) were measured twice and once a week, respectively. Student’s t-test was used to calculate statistical significance between Pso-treated and -untreated animals at each time point. *P<0.05, **P<0.01, ***P<0.001.