Figure 1.

Mutation spectrum identified in ulcerative colitis high-risk subjects by targeted sequencing. (A) Chromosomal distribution of mutations identified in nine UCHR-NP subjects. (B) Chromosomal distribution of mutations identified in nine UCHR-P subjects. (C) Base substitution pattern and distribution of transition and transversion observed in 18 UCHR subjects. (D) Distribution of mutation frequency in UCHR-NP and -P subjects. (E) Mutational signature analysis using somatic single base substitutions identified in UCHR subjects. A full color version of this figure is available at the British Journal of Cancer journal online.