Figure 8. Effect of tangeretin on the expressions of PI3K signaling pathway proteins. L1: Control; L2: OVA; L3: OVA + tangeretin (25 mg); L4: OVA + tangeretin (50 mg); L5: OVA + DEX. Molecular weights: Akt: 55 kDa; p-Akt: 55 kDa; GSK3β: 40 kDa; p-GSK3β: 40 kDa; PTEN: 50 kDa; mTORc1: 250 kDa; β-actin: 40 kDa (top). Relative expressions of PI3K/Akt pathway proteins by western blotting (bottom). Data are reported as means±SD, n=6. *P<0.05 vs control; #P<0.05 vs OVA; P<0.05, different small letters represent significant differences between experimental groups (one-way ANOVA followed by Duncan's multiple range test). OVA: ovalbumin; DEX: dexamethasone.
