Table 1.

Correlations and corresponding P values between modules and achieving sustained drug-free remission within sequenced CD4⁺ cells

The module eigengene, which is the first principal component of the expression matrix within the module of interest, was considered as the average gene expression profile and was used to test the correlation between each module and achieving sustained drug-free remission

^‡The modules with the highest significant correlation (shown in italic) were considered most relevant and were selected for further functional pathway analysis

^†The minimal number of genes per module was set at 20, except for the tocilizumab arm (n = 10)