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. 2017 Jan 18;72(7):646–653. doi: 10.1136/thoraxjnl-2016-208789

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This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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Cumulative incidence of lung cancer among 2576 high-risk smokers, and observed and predicted 6-year risk by AHRR (cg05575921) methylation extent quintiles. High risk was defined as predicted PLCO_M2012 6-year risk>1.3455%.²² AHRR, aryl hydrocarbon receptor repressor; PLCO_M2012, Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.