Table 2.
Laboratory parameters of 365 patients hospitalized with dengue
| All | Severe Dengue | Non-severe Dengue | p-value | ||||
|---|---|---|---|---|---|---|---|
| n | No. (% or IQR) | n | No. (% or IQR) | n | No. (% or IQR) | ||
| Duration of febrile phase (d) | 360 | 4.8 (3.8 - 5.8) | 21 | 5 (4.1 - 7.3) | 339 | 4.8 (3.8 - 5.8) | 0.170b |
| Phase at admission, febrile | 360 | 230 (63.90%) | 21 | 16 (76.20%) | 339 | 214 (63.10%) | 0.250a |
| Day of presentation (d) | 361 | 4.3 (3.2 - 5.3) | 22 | 4.2 (3.1 - 5.1) | 339 | 4.3 (3.2 - 5.4) | 0.570b |
| NS1 Ag | 356 | 288 (80.90%) | 22 | 20 (90.90%) | 334 | 268 (80.20%) | 0.270a |
| High-titre IgG | 360 | 160 (44.40%) | 22 | 11 (50.00%) | 338 | 149 (44.10%) | 0.660a |
| Admission Hct, median (IQR), % | 365 | 42 (39 - 46) | 22 | 41 (37 - 43) | 343 | 42 (39 - 46) | 0.160b |
| Admission CK, median (IQR), IU/L | 354 | 208 (103 - 409) | 19 | 212 (116 - 300) | 335 | 207 (103 - 424) | 0.760b |
| Admission AST, median (IQR), IU/L | 364 | 79 (47 - 135) | 22 | 231 (97 - 564) | 342 | 75 (47 - 128) | < 0.001b |
| Admission ALT, median (IQR), IU/L | 365 | 51 (29 - 100) | 22 | 122 (49 - 230) | 343 | 49 (28 - 91) | 0.003b |
| Nadir WBC, median (IQR), ×103/μL | 364 | 2.5 (1.9 - 3.6) | 22 | 2.8 (2 - 3.8) | 342 | 2.5 (1.9 - 3.6) | 0.540b |
| Nadir Platelet, median (IQR), ×103/μL | 364 | 41 (21 - 67) | 22 | 27 (10 - 49) | 342 | 42 (22 - 67) | 0.020b |
| Nadir Serum Albumin, median (IQR), g/L | 326 | 32 (30 - 36) | 21 | 27 (23 - 29) | 305 | 33 (30 - 36) | < 0.001b |
| Peak CK, median (IQR), IU/L | 103 | 429 (199 - 1044) | 10 | 404 (171 - 766) | 93 | 431 (206 - 1118) | 0.430b |
| Peak AST, median (IQR), IU/L | 338 | 123 (74 - 243) | 21 | 585 (144 - 1098) | 37 | 116 (73 - 223) | < 0.001b |
| Peak ALT, median (IQR), IU/L | 340 | 86 (41 - 175) | 22 | 225 (107 - 403) | 318 | 81 (39 - 162) | < 0.001b |
a Fisher’s exact test or Chi square test, as appropriate
b Mann-Whitney U test
c Chi-square for trend
IQR interquartile range, CK creatine kinase, AST aspartate transaminase, ALT alanine transaminase, WBC white blood cell count, AKI acute kidney injury