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. 2017 Jun 7;6(6):e48. doi: 10.1038/emi.2017.34

Table 3. Comparison of results using the bacteriological test results as ‘gold standard’ for TB diagnosis.

  T-SPOT.TB ELISpot-2351c P-value
Sensitivity 98.2% (56/57) 61.4% (35/57) 0.000
Specificity 94.6% (88/93) 91.4% (85/93) 0.388
Youden index 0.928 0.528  
Kappa value 0.916 0.554  

Note: 57 TB patients were diagnosed positive and 93 were diagnosed negative with the ‘gold standard’.